• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A fixation device (40) includes a member (26) defining at least two openings, and a suture (24) tied to the member by passing the suture through the at least two openings in the member to form two suture loops through which ends of the suture pass. The two suture loops are interconnected. A method of securing a tissue graft includes providing the fixation member, attaching the suture to a tissue graft, and adjusting the length of the suture between the fixation member and the tissue graft by pulling the suture.
    公开号:AU2013214999A1
    申请号:U2013214999
    申请日:2013-01-31
    公开日:2014-08-21
    发明作者:Alfred Rodrigue Berube Jr.；Michael Charles Ferragamo；Michael James Perriello
    申请人:Smith and Nephew Inc；
    IPC主号:A61B17-04
    专利说明:
    WO 2013/116573 PCT/US2013/024231 TISSUE GRAFT ANCHORING This invention relates to tissue graft anchoring. BACKGROUND An anterior cruciate ligament (ACL) that has ruptured and is non-repairable is generally replaced arthroscopically by a tissue graft. The tissue graft can be harvested from a portion of a patellar tendon having so called "bone blocks" at each end, and from the semitendonosis and gracilis. Alternatively, the tissue graft can be formed from synthetic materials or from a combination of synthetic and natural materials. The replacement tissue graft is implanted by securing one end of the tissue graft in a socket formed in a passage within the femur, and passing the other end of the graft through a passage formed in the tibia. Generally, sutures are used to affix each end of the tissue graft to a fastener (e.g., an interference screw or a post), which is then secured to the bone. It is also known to use a graft fixation member, e.g., a fixation button, to secure the tissue graft at the femoral cortex, as described in U.S. Pat. No. 5,306,301 ("the '301 patent") hereby incorporated by reference in its entirety. When using a fixation button, the femoral passage generally includes a relatively larger diameter portion for receiving the graft, and a smaller diameter, passing channel near the femoral cortex for receiving a length of suture that runs from the tissue graft to the fixation button. By measuring the total length of the femoral passage and the length of the larger diameter portion of the femoral passage, the surgeon determines the appropriate length of suture material for attaching the fixation button to the tissue graft. SUMMARY To increase the graft/channel interface in femoral fixation for cruciate repair the distance between a graft fixation member and the tendon construct is reduced. The ability to minimize this distance is generally limited by fixation member flipping 1 WO 2013/116573 PCT/US2013/024231 constraints, which results in less tendon in the femoral channel, or leads to making compromises in the size of the graft fixation member to accommodate the tendon and the flipping of the graft fixation member. According to one aspect, a method of securing a tissue graft includes providing a fixation member having a suture tied thereto by passing the suture through at least two openings in the fixation member to form two suture loops through which ends of the suture pass, attaching the suture to the tissue graft, and adjusting the length of the suture between the fixation member and the tissue graft by pulling the suture. Embodiments of this aspect may include one or more of the following features. The two suture loops are interconnected. Attaching the suture includes forming a loop of soft tissue of the tissue graft over the suture. Attaching the suture includes passing the suture through a bone block of the tissue graft followed by tying the suture to the fixation member. The method includes passing the fixation member, suture, and attached tissue graft through a bone passage, followed by adjusting the length of the suture between the fixation member and the tissue graft. According to another aspect, a fixation device includes a member defining at least two openings, and a suture tied to the member by passing the suture through the at least two openings in the member to form two suture loops through which ends of the suture pass. Embodiments of this aspect may include one or more of the following features. The two suture loops are interconnected. The member is elongated in a first dimension defining a length that extends between first and second ends of the member, and the member has a second dimension transverse to the first dimension that is smaller than the length. The member defines four, six, or seven holes. The details of one or more implementations are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the disclosure will be apparent from the description and drawings, and from the claims. 2 WO 2013/116573 PCT/US2013/024231 BRIEF DESCRIPTION OF THE DRAWINGS Figs. 1A and lB are illustrations of a tissue graft secured within the knee by a graft fixation member. Fig. 2 is another view of the knee joint of Fig. 1. Figs. 3-6 are perspective views of embodiments of fixation devices. Figs. 7A and 7B are perspective views of an additional embodiment of a fixation device. DETAILED DESCRIPTION Referring to Figs. 1A and iB, a knee joint has a tissue graft 10 (e.g., a patellar tendon graft (Fig. 1A) or a semitendonosis and gracilis graft (Fig. 1B)) implanted in an anterior cruciate ligament (ACL) repair and reconstruction procedure. Prior to implanting tissue graft 10, a notchplasty procedure is preferably performed to expand the intercondylar notch 12 of the femur bone. A femoral channel 14 for receiving one end of tissue graft 10 is then drilled from notch 12 a predetermined distance within the femur with a passing channel 16 of reduced diameter drilled further through the femur from femoral channel 14 to a region of femoral cortex 18. A tibial channel 20 for receiving the other end of tissue graft 10 is drilled from an anterior region of the tibia to a region near the opening of femoral channel 14. In the case of patellar tendon graft, one end of tissue graft 10 includes a bone block 22 which is shaped and sized in close conformity with femoral channel 14 to ensure optimal healing. A length of suture 24 has one end attached to bone block 22 and the other end secured at femoral cortex region 18 with a graft fixation member 26 of a fixation device 27. The suture 24 is attached to the graft fixation member 26 in a manner that permits the length of the suture 24 between the graft fixation member 26 and the tissue graft 10 to be adjusted prior to or after the graft 10 and the fixation member 26 have been positioned as shown in Figs. 1A and 1B. The other end of tissue graft 10 includes a second length of suture 28 which is attached to the tibia, for example, with a 3 WO 2013/116573 PCT/US2013/024231 fixation screw 30. A washer 32 either attached to or positioned under the head of fixation screw 30 helps in holding the suture in place when screw 30 is tightened. The graft fixation member 26 is positioned using pull threads (not shown) attached to the member. The pull threads are passed through the channels 14 and 16 from the notch 12 to the cortex 18 and used to pull the graft fixation member 26 through the channels 14 and 16 with a long axis of the graft fixation member aligned with the channels. After exiting the channel 16, the pull threads are used to flip the graft fixation member 26 so that the member 26 lies flat against the cortex. Referring to Fig. 2, length (L) of femoral channel 14 is selected by the surgeon in accordance with the length of bone block 22 and the desired insertion distance of tissue graft 10 within the femur. The span of suture 24, designated as SS, is approximately that of passing channel 16 so that the sum of the desired insertion length (L) and span of suture (SS) is the measured total length (TL) from the opening of femoral channel 14 to the opening at femoral cortex 18. Each of these dimensions is measured prior to implanting the tissue graft so that during the implantation procedure, the surgeon, under arthroscopic observation, can be assured that tissue graft 10 has been properly positioned within femoral channel 14. The ability to adjust the length of the suture 24 allows the length of the suture span (SS) to be minimized, only being limited by the desired length of passing channel 16. There is a minimum length of the suture 24 that is necessary during passage of the graft fixation member 26 through the channel 14, 16 to allow the member 26 to be positioned in alignment with the channels. Once the graft fixation member 26 is located against the femoral cortex 18, the length of the suture 24 can be shortened by pulling on the suture to maximize the amount of the tissue graft 10 that is located within the femoral channel 14. The suture 24 is a woven or braided suture, for example, #5 Ultrabraid suture, attached to the graft fixation member 26 in a loop and knot configuration to form a fixation device 40. Referring to Fig. 3, the graft fixation member 26 is elongated in a first dimension defining a length, L, that extends between a first end 42 and a second end 44 of the member 26, a second dimension transverse to the first dimension that has a width, W, smaller than the length, L, and a third dimension transverse to the first and 4 WO 2013/116573 PCT/US2013/024231 second dimensions that has a height, H, small than the length, L. The graft fixation member has a bone contacting side 46 and an opposite side 48. Extending between the sides 46, 48 are four holes 50, 52, 54 and 56. The holes 50 and 56 receive the passing sutures, not shown. The suture 24 is a single length of suture passed through holes 52 and 54 to form two interconnecting loops 60, 62 through which ends 64, 66, respectively, of the suture 24 are passed, created a knot 76 and a loop 68 of three suture loops 70, 72, and 74. To form the loop and knot configuration, for example, the end 66 of the suture 24 is passed down through hole 54 and up through hole 52, creating loop 70; folded over on itself, around the length of suture extending up from hole 54, and passed back down hole 52, creating loop 60; passed up through hole 54, creating loop 72; passed through loop 60, folded over on itself, and passed back down hole 54, creating loop 62 interconnected with loop 60; passed up through hole 52, creating loop 74; and then passed through loop 62. By pulling on the ends 64, 66 of the suture 24, the length of the loop 68 can be adjusted, for example, from a minimum that equals the distance between the holes 52 and 54 to about 30mm, such that, with the tissue graft 10 attached the suture 24, the distance between the graft fixation member 26 and the tissue graft 10 can be adjusted between 0mm and about 15mm. When the fixation device 40 is used with a semitendonosis and gracilis graft (Fig. IB), the suture 24 can be provided to the surgeon pre-tied to the graft fixation member 26, and operating room personnel attach the tissue graft to the fixation device 40 by passing the tissue graft through the suture loop 68. When a patellar tendon graft (Fig. 1A) is used, operating room personnel form the loop and knot configuration by passing the suture through the bone block of the graft while forming the loop and knot configuration. The distance between the graft fixation member 26 and the tissue graft 10 can be adjusted while the graft/fixation member construct is in the femoral tunnel. Alternatively, the distance is determined by the surgeon prior to placing the graft. Once the graft fixation member 26 and the tissue graft 10 are positioned in the knee with the desired length of the suture 24, tension placed on the suture by the tissue graft acts to secure the loop and knot configuration. 5 WO 2013/116573 PCT/US2013/024231 The length, width and height of the fixation member 26, is for example, 12mm x 4mm x 1.5mm. Other embodiments are within the scope of the following claims. For example, referring to Fig. 4, the suture loops 70, 72 and 73 can be twisted. Referring to Fig. 5, the suture loops 70 and 74 can be tightened against the bone contacting side 46 of the graft fixation member 26 such that in use the tissue graft is only attached to loop 72. The graft fixation member 26a of Fig. 6 includes six holes with the suture 24 being passed through four central holes to form loops 70, 72 and 74, and knot 76. The graft fixation member 26b of Fig. 7A and 7B includes seven holes with the suture 24 being passed through five central holes 80, 82, 84, 86 and 88. The form the suture construct, the suture end 66 is passed down through hole 88, up through hole 86, over the suture extending up from hole 88, down through hole 84, looped and passed back up through hole 84, down through hole 82, up through hole 80, and through the loop formed between holes 84 and 82. The graft fixation member can be modified to aid flipping of the member by providing open or closed ends, and variation in thickness, length or width. To aid in positioning the graft fixation member at the end of the channel, the member can have a banana shape or modifications such as rectangular, triangular or other geometric shapes. To aid in strength of pull out the thickness of the graft fixation member between the holes in the member can be adjusted. This section of the graft fixation member between the holes can be modified by increasing or reducing its thickness to open the space for and reduce the distance between the graft fixation member and the tissue graft. The graft fixation member can include only a single opening with the suture tied to graft fixation member by passing the suture through the single opening in the member to form two suture loops through which ends of the suture pass. Other implementations are within the scope of the following claims. 6
    权利要求:
    Claims (12)
    [1] 1. A method of securing a tissue graft comprising: providing a fixation member having a suture tied thereto by passing the suture through at least two openings in the fixation member to form two suture loops through which ends of the suture pass; attaching the suture to the tissue graft; and adjusting the length of the suture between the fixation member and the tissue graft by pulling the suture.
    [2] 2. The method of claim 1 wherein the providing includes the two suture loops being interconnected.
    [3] 3. The method of claim 1 wherein attaching the suture comprises forming a loop of soft tissue of the tissue graft over the suture.
    [4] 4. The method of claim 1 wherein attaching the suture comprises passing the suture through a bone block of the tissue graft followed by tying the suture to the fixation member.
    [5] 5. The method of claim 1 comprising passing the fixation member, suture, and attached tissue graft through a bone passage, followed by adjusting the length of the suture between the fixation member and the tissue graft.
    [6] 6. A fixation device comprising: a member defining at least one opening; and a suture tied to the member by passing the suture through the at least one opening in the member to form two suture loops through which ends of the suture pass.
    [7] 7. The fixation device of claim 6 wherein the two suture loops are interconnected. 7 WO 2013/116573 PCT/US2013/024231
    [8] 8. The fixation device of claim 6 wherein the member is elongated in a first dimension defining a length that extends between first and second ends of the member, the member having a second dimension transverse to the first dimension that is smaller than the length.
    [9] 9. The fixation device of claim 6 wherein the member defines two openings.
    [10] 10. The fixation device of claim 6 wherein the member defines four openings.
    [11] 11. The fixation device of claim 6 wherein the member defines six openings.
    [12] 12. The fixation device of claim 6 wherein the member defines seven openings. 8
    类似技术:
    公开号 | 公开日 | 专利标题
    US9561027B2|2017-02-07|Tissue graft anchoring
    AU2012253446B2|2016-10-20|Tissue graft anchoring
    AU2013235641B2|2017-07-27|Tissue graft anchoring
    US10856967B2|2020-12-08|Implant having adjustable filament coils
    US5769894A|1998-06-23|Graft attachment device and method of attachment
    US6533802B2|2003-03-18|Endobutton continuous loop for bone-tendon-bone
    EP1108401B1|2005-09-07|A ligament graft fixation device
    US9629707B2|2017-04-25|Attachment device to attach tissue graft
    US20080208204A1|2008-08-28|Intraarticular graft length gauge
    WO2020109817A1|2020-06-04|Implant assembly and associated methods of manufacturing
    同族专利:
    公开号 | 公开日
    US9561027B2|2017-02-07|
    JP2015507952A|2015-03-16|
    KR20140117539A|2014-10-07|
    RU2014133969A|2016-03-20|
    US20130197580A1|2013-08-01|
    US20150112385A1|2015-04-23|
    ZA201405599B|2015-10-28|
    CN104394777B|2016-12-21|
    US8926662B2|2015-01-06|
    IN2014DN06484A|2015-06-12|
    CN104394777A|2015-03-04|
    EP2809242A1|2014-12-10|
    WO2013116573A1|2013-08-08|
    RU2621263C2|2017-06-01|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US3580256A|1969-06-30|1971-05-25|Jack E Wilkinson|Pre-tied suture and method of suturing|
    US4605414A|1984-06-06|1986-08-12|John Czajka|Reconstruction of a cruciate ligament|
    GB8525565D0|1985-10-17|1985-11-20|Speedhom B B|Surgical replacement of ligaments|
    EP0328401A1|1988-02-11|1989-08-16|Unisearch Limited|Anastomosis augmentation device|
    FR2638349B1|1988-10-28|1990-12-28|Breard Francis|PROSTHESIS OF TENDON AND PARTICULARLY SHOULDER HEAD|
    US5139520A|1990-01-31|1992-08-18|American Cyanamid Company|Method for acl reconstruction|
    US5405352A|1991-04-09|1995-04-11|Weston; Peter V.|Suture knot, method for its formation and use, and knot forming apparatus|
    US5217470A|1991-04-29|1993-06-08|Weston Peter V|Apparatuses and methods for formation and use of a slipknot as a surgical suture knot|
    EP0520177B1|1991-05-24|1995-12-13|Synthes AG, Chur|Resorbable tendon and bone augmentation device|
    US5234445A|1992-09-18|1993-08-10|Ethicon, Inc.|Endoscopic suturing device|
    AT161160T|1992-11-17|1998-01-15|Smith & Nephew Inc|DEVICE FOR FASTENING SEAM MATERIAL|
    US5306301A|1993-02-11|1994-04-26|American Cyanamid Company|Graft attachment device and method of using same|
    US5449367A|1993-08-02|1995-09-12|Kadry; Othman|Pre-tied knot for surgical use and method of using same|
    US5451203A|1994-07-29|1995-09-19|Orthopedic Systems, Inc.|Traction mechanism|
    GB9510637D0|1995-05-25|1995-07-19|Ellis Dev Ltd|Device for the repair of the rotator cuff of the shoulder|
    FR2743294B1|1996-01-05|1998-04-03|Ethnor|IMPLANTABLE BONE ANCHORING DEVICE OF A LIGAMENTARY OR OSTEO-LIGAMENTARY TRANSPLANT, PARTICULARLY FOR THE REPAIR OF THE ANTERIOR CROSS LIGAMENT OF THE KNEE|
    FR2745710B1|1996-03-11|1998-05-29|Rippstein Pascal Francois|TENDON PASSING DEVICE|
    US5718717A|1996-08-19|1998-02-17|Bonutti; Peter M.|Suture anchor|
    GB9620046D0|1996-09-26|1996-11-13|Neoligaments|Attachment device for use in the implantation of prosthetic ligament|
    DE69734606T2|1996-11-21|2006-08-03|Ethicon, Inc.|DEVICE FOR FIXING BODY-FREE OR ARTIFICIAL TENANTS IN BONES|
    US5769894A|1997-02-05|1998-06-23|Smith & Nephew, Inc.|Graft attachment device and method of attachment|
    AUPO530997A0|1997-02-25|1997-03-20|Esnouf, Philip Stuart|Surgical aid for connective tissue grafting and method for employing same|
    FR2760185B1|1997-02-28|1999-05-14|Laurent Fumex|SURGICAL BONE AND ANCILLARY ANCHORING DEVICE FOR ITS PLACEMENT|
    US5893592A|1997-04-08|1999-04-13|Ethicon Endo-Surgery, Inc.|Partially tied surgical knot|
    US20020165611A1|1998-12-22|2002-11-07|Robert-Jan Enzerink|Graft material convenience package|
    US6203572B1|1999-02-09|2001-03-20|Linvatec Corporation|Device and method for ligament reconstruction|
    US6319252B1|1999-07-23|2001-11-20|Mcdevitt Dennis|System and method for attaching soft tissue to bone|
    US7887551B2|1999-12-02|2011-02-15|Smith & Nephew, Inc.|Soft tissue attachment and repair|
    GB9929599D0|1999-12-15|2000-02-09|Atlantech Medical Devices Limi|A graft suspension device|
    US6296659B1|2000-02-29|2001-10-02|Opus Medical, Inc.|Single-tailed suturing method and apparatus|
    US6746483B1|2000-03-16|2004-06-08|Smith & Nephew, Inc.|Sheaths for implantable fixation devices|
    US6652561B1|2000-10-13|2003-11-25|Opus Medical, Inc|Method and apparatus for attaching connective tissues to bone using a perforated suture anchoring device|
    US6506197B1|2000-11-15|2003-01-14|Ethicon, Inc.|Surgical method for affixing a valve to a heart using a looped suture combination|
    US6733506B1|2000-11-16|2004-05-11|Ethicon, Inc.|Apparatus and method for attaching soft tissue to bone|
    GB2370227B|2000-11-21|2002-11-06|Ahmed Mohamed Hosny Khashaba|Khashaba Tensioner 1 |
    US6533802B2|2001-05-16|2003-03-18|Smith & Nephew, Inc.|Endobutton continuous loop for bone-tendon-bone|
    US6716234B2|2001-09-13|2004-04-06|Arthrex, Inc.|High strength suture material|
    AU2002255144A1|2002-05-03|2003-11-17|Ahmed Mohamed Hosny Khashaba|Ligament tensioning device|
    RU2220665C1|2002-06-13|2004-01-10|Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова|Method for fixing free and replaced cutaneous transplants at plastic surgery in orbital and paraorbital areas|
    WO2004082724A2|2003-03-18|2004-09-30|Opus Medical Inc.|Optimized suture braid|
    US7722644B2|2003-06-11|2010-05-25|Medicine Lodge, Inc.|Compact line locks and methods|
    US7357810B2|2003-12-18|2008-04-15|Ethicon, Inc.|High strength suture with absorbable core and suture anchor combination|
    US7717929B2|2003-12-19|2010-05-18|Radi Medical Systems Ab|Technique for securing a suture|
    US20050251159A1|2004-05-07|2005-11-10|Usgi Medical Inc.|Methods and apparatus for grasping and cinching tissue anchors|
    US7736378B2|2004-05-07|2010-06-15|Usgi Medical, Inc.|Apparatus and methods for positioning and securing anchors|
    US8088146B2|2004-06-14|2012-01-03|Teleflex Medical Incorporated|High-strength suture|
    US8361113B2|2006-02-03|2013-01-29|Biomet Sports Medicine, Llc|Method and apparatus for coupling soft tissue to a bone|
    US8137382B2|2004-11-05|2012-03-20|Biomet Sports Medicine, Llc|Method and apparatus for coupling anatomical features|
    US8298262B2|2006-02-03|2012-10-30|Biomet Sports Medicine, Llc|Method for tissue fixation|
    US8118836B2|2004-11-05|2012-02-21|Biomet Sports Medicine, Llc|Method and apparatus for coupling soft tissue to a bone|
    US8088130B2|2006-02-03|2012-01-03|Biomet Sports Medicine, Llc|Method and apparatus for coupling soft tissue to a bone|
    US8652172B2|2006-02-03|2014-02-18|Biomet Sports Medicine, Llc|Flexible anchors for tissue fixation|
    US7905904B2|2006-02-03|2011-03-15|Biomet Sports Medicine, Llc|Soft tissue repair device and associated methods|
    US7857830B2|2006-02-03|2010-12-28|Biomet Sports Medicine, Llc|Soft tissue repair and conduit device|
    CA2603652A1|2005-04-01|2006-10-12|The Regents Of The University Of Colorado|A graft fixation device and method|
    US8951285B2|2005-07-05|2015-02-10|Mitralign, Inc.|Tissue anchor, anchoring system and methods of using the same|
    US7972292B2|2005-07-06|2011-07-05|Percutaneous Systems, Inc.|Methods and apparatus for deploying ureteral stents|
    US8323338B2|2005-12-22|2012-12-04|Smith & Nephew, Inc.|Tissue graft fixation|
    US20070156174A1|2006-01-03|2007-07-05|Arthrotek, Inc.|Method and apparatus for repairing a meniscus|
    US7959650B2|2006-09-29|2011-06-14|Biomet Sports Medicine, Llc|Adjustable knotless loops|
    US7905903B2|2006-02-03|2011-03-15|Biomet Sports Medicine, Llc|Method for tissue fixation|
    US7749250B2|2006-02-03|2010-07-06|Biomet Sports Medicine, Llc|Soft tissue repair assembly and associated method|
    US8298284B2|2006-03-21|2012-10-30|Arthrex, Inc.|Whip stitched graft construct and method of making the same|
    US8852250B2|2006-05-18|2014-10-07|Linvatec Corporation|Graft fixation implant|
    US7658751B2|2006-09-29|2010-02-09|Biomet Sports Medicine, Llc|Method for implanting soft tissue|
    US7963983B2|2006-10-17|2011-06-21|Arthroscopic Innovations Llc|Fixation device for surgical repair|
    US7875058B2|2007-01-17|2011-01-25|Arthrex, Inc.|Bunion repair using suture-button construct|
    US7875057B2|2007-01-19|2011-01-25|Arthrex, Inc.|Method and suture-button construct for stabilization of cranial cruciate ligament deficient stifle|
    US20090036905A1|2007-01-30|2009-02-05|Reinhold Schmieding|Method of tissue fixation using cinch stitching|
    EP1958591B1|2007-02-13|2016-05-11|Arthrex, Inc.|Intraarticular graft length gauge|
    US9017381B2|2007-04-10|2015-04-28|Biomet Sports Medicine, Llc|Adjustable knotless loops|
    US7771455B2|2007-08-31|2010-08-10|Ken Christopher G M|Closure medical device|
    US20100023056A1|2008-07-23|2010-01-28|Guided Delivery Systems Inc.|Tether-anchor assemblies|
    US9314238B2|2008-11-03|2016-04-19|Syntorr, Inc.|T-type suture anchor|
    US8529610B2|2008-12-09|2013-09-10|Smith & Nephew, Inc.|Tissue repair assembly|
    US8460379B2|2009-03-31|2013-06-11|Arthrex, Inc.|Adjustable suture button construct and methods of tissue reconstruction|
    US8439976B2|2009-03-31|2013-05-14|Arthrex, Inc.|Integrated adjustable button-suture-graft construct with two fixation devices|
    US8460350B2|2009-06-19|2013-06-11|Arthrex, Inc.|Graft protection mesh and fixation technique|
    US8814903B2|2009-07-24|2014-08-26|Depuy Mitek, Llc|Methods and devices for repairing meniscal tissue|
    US8828053B2|2009-07-24|2014-09-09|Depuy Mitek, Llc|Methods and devices for repairing and anchoring damaged tissue|
    US9757132B2|2010-03-24|2017-09-12|Biorez, Inc.|Mechanically competent scaffold for rotator cuff and tendon augmentation|
    US20120109194A1|2010-10-28|2012-05-03|Linvatec Corporation|Suspensory graft fixation with adjustable loop length|
    EP2455001B1|2010-11-17|2020-07-22|Arthrex, Inc.|Adjustable suture-button constructs for ligament reconstruction|
    US10245016B2|2011-10-12|2019-04-02|Arthrex, Inc.|Adjustable self-locking loop constructs for tissue repairs and reconstructions|US7722644B2|2003-06-11|2010-05-25|Medicine Lodge, Inc.|Compact line locks and methods|
    WO2012040627A1|2010-09-24|2012-03-29|Medicinelodge, Inc. Dba Imds Co-Innovation|System for intra -operative tension and fixation of zipknot acl fixation|
    US8926661B2|2011-06-02|2015-01-06|Smith & Nephew, Inc.|Surgical fastening|
    US11253252B2|2012-07-30|2022-02-22|Conextions, Inc.|Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone|
    US10835241B2|2012-07-30|2020-11-17|Conextions, Inc.|Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone|
    US9427309B2|2012-07-30|2016-08-30|Conextions, Inc.|Soft tissue repair devices, systems, and methods|
    US9974643B2|2013-03-11|2018-05-22|Medos International Sàrl|Implant having adjustable filament coils|
    US10052094B2|2013-03-11|2018-08-21|Medos International Sàrl|Implant having adjustable filament coils|
    US9284668B2|2013-03-14|2016-03-15|Medos International Sárl|Continuous braided closed loop implant|
    US9757113B2|2013-07-31|2017-09-12|Medos International Sàrl|Adjustable graft fixation device|
    US10405968B2|2013-12-11|2019-09-10|Medos International Sarl|Implant having filament limbs of an adjustable loop disposed in a shuttle suture|
    WO2015138760A1|2014-03-12|2015-09-17|Conextions, Inc.|Soft tissue repair devices, systems, and methods|
    GB2531556A|2014-10-22|2016-04-27|Xiros Ltd|An elongate guide element for an implant|
    US10925716B2|2015-02-25|2021-02-23|Smith & Nephew, Inc.|Closed loop suture for anchoring tissue grafts|
    KR101674544B1|2015-01-14|2016-11-09|중원대학교 산학협력단|adjustable suture button construct for Anterior Cruciate Ligament reconstruction|
    AU2016364969B2|2015-12-04|2021-09-16|Crossroads Extremity Systems, Llc|Devices for anchoring tissue|
    US10702260B2|2016-02-01|2020-07-07|Medos International Sàrl|Soft tissue fixation repair methods using tissue augmentation scaffolds|
    WO2017142860A1|2016-02-16|2017-08-24|Smith & Nephew, Inc.|Graft suspension device|
    JP6843969B2|2016-08-25|2021-03-17|アースレックス インコーポレイテッド|Surgical fixation system|
    US10973509B2|2017-12-20|2021-04-13|Conextions, Inc.|Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone|
    KR101884614B1|2016-10-11|2018-08-02|신일제약주식회사|Fab fragment and uses thereof|
    CN106510908B|2016-12-01|2018-03-27|周大勇|A kind of interior planting apparatus rebuild for cruciate ligaments of knee joint|
    US10646327B2|2017-02-09|2020-05-12|Arthrex, Inc.|Self-locking suture constructs and methods of tissue fixation|
    US10575842B2|2017-02-09|2020-03-03|Arthrex, Inc.|Knotless self-locking anchor constructs and methods of tissue fixation|
    CA3055945A1|2017-03-13|2018-09-20|Arthrex, Inc.|Surgical fixation systems and methods|
    US10758224B2|2017-03-27|2020-09-01|Trimed, Incorporated|System and method controlling a relationship between first and second bodies on a person|
    CN107028683A|2017-03-31|2017-08-11|上海长海医院|A kind of coracoclavicular ligament reconstructing device|
    WO2019033480A1|2017-08-17|2019-02-21|北京德益达美医疗科技有限公司|Dynamically pressurized ligament reconstruction system|
    WO2019219548A1|2018-05-16|2019-11-21|Zurimed Technologies Ag|Single strand self-locking suspension device for medical use|
    GB201819426D0|2018-11-29|2019-01-16|Xiros Plc|Implant assembly and associated methods|
    WO2021195460A1|2020-03-27|2021-09-30|Edwards Lifesciences Corporation|Suture tension distribution|
    CN112315529B|2020-11-30|2021-09-21|上海傲派医疗科技有限公司|Loop and manufacturing method thereof|
    CN112472266A|2020-12-10|2021-03-12|江苏爱厚朴医疗器械有限公司|Ligament tibia insertion avulsion fracture fixing device and matched operation method thereof|
    CN112617924B|2020-12-31|2021-09-07|上海傲派医疗科技有限公司|Medical loop ring and manufacturing method thereof|
    法律状态:
    2016-07-21| MK1| Application lapsed section 142(2)(a) - no request for examination in relevant period|
    优先权:
    申请号 | 申请日 | 专利标题
    US13/363,575||2012-02-01||
    US13/363,575|US8926662B2|2012-02-01|2012-02-01|Tissue graft anchoring|
    PCT/US2013/024231|WO2013116573A1|2012-02-01|2013-01-31|Tissue graft anchoring|
    [返回顶部]